Two interesting cases of gestational trophoblastic disease with methotrexate failure
نویسندگان
چکیده
منابع مشابه
Unusual presentation of gestational trophoblastic neoplasm: Report of two cases
Abstract: Gestational Trophoblastic Neoplasm (GTN) is among rare human tumors which can be observed with widespread metastasis. Two young patients with emergent neurologic symptoms with no gynecological problems are presented in this report. GTN was later diagnosed in both cases with brain metastasis. The first case: A 22 years old patient, admitted to the infectious disease ward, with probab...
متن کاملComparison of Two Therapeutic Regimens: Methotrexate-Folinic Acid (8 days) and Weekly Methotrexate in Patients with Low risk Gestational Trophoblastic neoplasia
Background: Methotrexate is used in the treatment of Low-risk Gestational Trophoblastic Neoplasia. The purpose of this study was to compare the therapeutic responses and side effects of two therapeutic methods which were prescribed for patients suffering from Low-risk Gestational Trophoblastic Neoplasia. One method was the daily use of Methotrexate-Folic Acid (for 8 da...
متن کاملGestational Trophoblastic Disease
In partial molar pregnancies, the trophoblast cells have three sets of chromosomes (triploid). Two sperm are believed to fertilise the ovum at the same time, leading to one set of maternal and two sets of paternal chromosomes. Around 10% of partial moles are tetraploid or mosaic in nature. There is usually evidence of fetal tissue or fetal blood cells in a partial molar pregnancy. An embryo may...
متن کاملGestational trophoblastic disease.
BACKGROUND Molar pregnancy represents a significant burden of disease on the spectrum of Gestational Trophoblastic Disease (GTD). The incidence appears to be quite high in South Asia. The objective of this study was to determine the frequency of GTD, and clinical presentation, management and outcome of patients with molar pregnancy. METHODS This retrospective, descriptive study was conducted ...
متن کاملunusual presentation of gestational trophoblastic neoplasm: report of two cases
abstract: gestational trophoblastic neoplasm (gtn) is among rare human tumors which can be observed with widespread metastasis. two young patients with emergent neurologic symptoms with no gynecological problems are presented in this report. gtn was later diagnosed in both cases with brain metastasis. the first case: a 22 years old patient, admitted to the infectious disease ward, with probable...
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ژورنال
عنوان ژورنال: International Journal of Reproduction, Contraception, Obstetrics and Gynecology
سال: 2016
ISSN: 2320-1770
DOI: 10.18203/2320-1770.ijrcog20163027